But they noted Dallas could easily get caught looking ahead to a Week 16 matchup with the NFC East-leading Eagles.Ĭatch the full episode (and subscribe for daily NFL talk) right here.

The Cowboys (-4.5) should be favored against the Jaguars, the guys agreed, even in light of Trevor Lawrence's recent tear.

But Brinson has concerns: 'Can Jared Goff go win that game in the cold weather if the Lions can't run?'

Both guys are leaning Lions in a pick 'em matchup with the Jets, unsure of Mike White's status as New York's battered signal-caller.

Sully is also leaning San Francisco, but he's more wary of a potential Brock Purdy slip-up in a 'kitchen-sink game' for the home underdogs.

Brinson is buying the 49ers (-3) as road favorites on Thursday night, citing the Seahawks' porous run defense (which has allowed an NFL-worst 209 yards per game the last four weeks) as a major concern for Seattle.Which teams are the safest bets? Which point spreads are suspicious? Here are some highlights:

Tyler Sullivan joined Will Brinson on Wednesday's 'Pick Six NFL Podcast' to break down all the biggest Week 15 matchups from a betting perspective.

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